Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nutritional factors and cellular immune responses.

Y Kishino1, S Moriguchi

  • 1Department of Nutrition, School of Medicine, University of Tokushima, Japan.

Nutrition and Health
|January 1, 1992
PubMed
Summary

Adequate protein and specific vitamins (A and E) are crucial for maintaining a strong immune response in rats, particularly for lung health and fighting infection and cancer.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multidomain Intervention Trial for Preventing Cognitive Decline among Older Adults with Type 2 Diabetes: J-MIND-Diabetes.

The journal of prevention of Alzheimer's disease·2024
Same author

Association between Reduction of Muscle Mass and Faster Declines in Global Cognition among Older People: A 4-Year Prospective Cohort Study.

The journal of nutrition, health & aging·2023
Same author

Cross-Sectional Associations of Sarcopenia and Its Components with Neuropsychological Performance among Memory Clinic Patients with Mild Cognitive Impairment and Alzheimer's Disease.

The Journal of frailty & aging·2022
Same author

Blockade of the K<sub>ATP</sub> channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy.

Molecular psychiatry·2016
Same author

Rivastigmine improves hippocampal neurogenesis and depression-like behaviors via 5-HT1A receptor stimulation in olfactory bulbectomized mice.

Neuroscience·2014
Same author

Effect of alanylglutamine-enriched infusion on tumor growth and cellular immune function in rats.

Amino acids·2013

Area of Science:

  • Nutrition and immunology
  • Pulmonary health
  • Cellular immunity

Background:

  • Nutritional status significantly impacts immune function across all age groups, affecting susceptibility to infections and cancer.
  • The elderly and young children are particularly vulnerable to immune system dysregulation due to nutritional factors.

Purpose of the Study:

  • To investigate the impact of varying dietary intakes on immune cells in rat lungs.
  • To determine the role of protein and specific vitamins (A and E) in modulating immune responses against pulmonary threats.

Main Methods:

  • Rats of various ages were subjected to controlled dietary regimens with different levels of food and nutrient intake.
  • Immune cell populations, specifically the macrophage-lymphocyte series in lung tissue, were analyzed.
  • The function of alveolar macrophages was assessed following supplementation with vitamins A and E.

Main Results:

  • A well-balanced diet with adequate protein (20-40%) was essential for sustaining high immune response levels in rats, irrespective of age.
  • Supplemental intake of vitamins A and E significantly enhanced the functional activity of alveolar macrophages.
  • Fat-soluble vitamins may reach the lungs via the lymphatic system, influencing immune cell function.

Conclusions:

  • Dietary protein is fundamental for robust immune function and maintaining immune cell health in the lungs.
  • Vitamins A and E play a critical role in activating alveolar macrophages, potentially offering protection against pulmonary infections and cancer.
  • Optimizing nutrition, including adequate protein and specific vitamins, is vital for bolstering lung immunity.

Related Experiment Videos