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Updated: Jun 18, 2026

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A Protocol for Detecting and Scavenging Gas-phase Free Radicals in Mainstream Cigarette Smoke
Published on: January 2, 2012
POLONIUM-210: A VOLATILE RADIOELEMENT IN CIGARETTES.
Summary
Polonium-210 (Po-210) in tobacco smoke delivers a significant radiation dose to the lungs of smokers. This internal radiation exposure may contribute to the development of bronchial cancer in individuals who smoke regularly.
Area of Science:
- Environmental Health
- Radiation Biology
- Oncology
Background:
- Polonium-210 (Po-210) is a naturally occurring radioactive isotope found as a contaminant in tobacco plants.
- Alpha particle emission from Po-210 results in internal radiation exposure when inhaled.
- Tobacco smoking is a major risk factor for bronchial cancer.
Purpose of the Study:
- To quantify the radiation dose to the bronchial epithelium from inhaled Polonium-210 in cigarette smoke.
- To assess the potential contribution of Po-210 radiation to the development of bronchial cancer in smokers.
Main Methods:
- Calculation of radiation dose to bronchial epithelium based on Po-210 content in tobacco smoke.
- Comparison of Po-210 radiation dose with background radiation dose.
Main Results:
- Smokers inhaling two packs of cigarettes daily receive a radiation dose from Po-210 that is at least seven times higher than background sources.
- Localized areas of the bronchial epithelium may receive doses of 1000 rem or more over 25 years from Po-210.
- The radiation dose from inhaled Po-210 is significant.
Conclusions:
- Radiation from Polonium-210 in cigarette smoke is a significant factor in the genesis of bronchial cancer.
- Reducing Po-210 exposure from tobacco smoke could mitigate cancer risk for smokers.
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