Related Experiment Videos
Carcinoma arising in a dentinogenic ghost cell tumor
B P McCoy1, M K O Carroll, J M Hall
1Department of Oral Diagnosis and Patient Services, Medical College of Georgia School of Dentistry, Augusta.
Oral Surgery, Oral Medicine, and Oral Pathology
|September 1, 1992
Summary
A rare odontogenic ghost cell tumor was diagnosed in a teenage girl with a nonhealing jaw lesion. Surgical removal led to a disease-free outcome, highlighting successful treatment for this aggressive odontogenic tumor.
Area of Science:
- Oral and Maxillofacial Surgery
- Oncology
- Pathology
Background:
- Odontogenic ghost cell tumors are rare jaw neoplasms.
- Early diagnosis and treatment are crucial for favorable outcomes.
Observation:
- A 13-year-old female presented with a 2-year history of a nonhealing extraction site.
- Radiographs showed a large, irregular mixed radiolucent/radiopaque lesion in the maxilla.
- Microscopic analysis revealed features of an odontogenic ghost cell tumor with anaplastic changes.
Findings:
- The lesion exhibited irregular dentinoid material and odontogenic epithelium with ghost cell keratinization.
- The tumor demonstrated aggressive features, occupying a significant portion of the maxilla and crossing the midline.
Implications:
- Complete surgical excision, such as hemimaxillectomy, is essential for managing aggressive odontogenic ghost cell tumors.
- This case highlights the importance of thorough histopathological examination for accurate diagnosis and treatment planning.
- Long-term follow-up is necessary to ensure no recurrence of the disease.