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[Stress and susceptibility to infection]
W Kaulfersch1, R Kurz, W Hitzig
1Universitäts-Kinderklinik Graz, Osterreich.
Padiatrie Und Padologie
|January 1, 1992
Summary
Stress significantly impacts the human immune system, affecting various immune responses. This is due to complex regulatory feedback between the immune and central nervous systems.
Area of Science:
- Neuroimmunology
- Psychoneuroimmunology
- Stress Physiology
Background:
- The human immune system is influenced by various stressors.
- Clinical and experimental studies investigate these influences.
- The relevance to disease onset, progression, and outcomes is under ongoing research.
Purpose of the Study:
- To explore the multifaceted impact of stressors on the immune system.
- To elucidate the regulatory mechanisms linking stress and immune function.
- To understand the role of neuro-immune interactions in disease.
Main Methods:
- Review of clinical and experimental studies.
- Analysis of regulatory feedback systems between the central nervous system and immune system.
- Examination of stressor coordination and psychological influences.
Main Results:
- Stress influences multiple aspects of immune responses.
- Immune system sensitivity to stress is linked to central nervous system interactions.
- Reciprocal regulatory influences form a feedback system.
Conclusions:
- Stress significantly modulates immune system activity.
- The central nervous system and immune system are intricately connected.
- These neuro-immune interactions are crucial for managing infections and inflammatory diseases.