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Hairy cell leukemia and factor VIII inhibitor: a case report
A Komminoth1, P Dufour, J P Bergerat
1Service d'Onco-Hématologie, CHU Hautepierre, Strasbourg, France.
Nouvelle Revue Francaise D'Hematologie
|January 1, 1992
Abstract:
Acquired factor VIII inhibitors are usually described in hemophilia A, although some cases have been documented in chronic inflammatory diseases and malignant tumors. We report here the first case of a factor VIII inhibitor appearing in the course of hairy cell leukemia. Interferon therapy over a 5 month period led to complete remission of leukemia with parallel disappearance of the acquired factor VIII inhibitor.