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Estimating worker exposure for pesticide registration
1Department of Occupational Toxicology, TNO Medical Biological Laboratory, Rijswijk, The Netherlands.
Reviews of Environmental Contamination and Toxicology
|January 1, 1992
Summary
Worker pesticide exposure models vary significantly due to differing databases and statistical methods. Considering multiple models enhances the representativity of predicted exposure levels for risk assessment.
Area of Science:
- Agricultural Science
- Environmental Health
- Risk Assessment
Background:
- Pesticide registration requires estimating worker exposure levels.
- Various worker exposure models exist in Europe and North America.
- These models estimate potential inhalation and dermal exposure.
Purpose of the Study:
- To compare and discuss different worker exposure models.
- To analyze the reasons for output variations between models.
- To provide recommendations for improving exposure estimations.
Main Methods:
- Comparative analysis of European and North American worker exposure models.
- Discussion of model outputs for inhalation and dermal exposure.
- Identification of factors influencing model variability.
Main Results:
- Model outputs for estimated exposure levels differ significantly.
- Variability is attributed to distinct underlying databases (equipment, farm size).
- Differences in statistical methods (geometric mean vs. 90-percentile) also contribute to variations.
Conclusions:
- Worker exposure model outputs are not uniform.
- A combination of relevant parts from all models is recommended.
- This approach increases the representativity of predicted exposure levels for risk assessment.