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Related Experiment Videos

[Patients returning after transplantation].

A Colombi1, R Martin, M Lampe

  • 1Nierenstation, Kantonsspital Luzern.

Schweizerische Medizinische Wochenschrift
|September 26, 1992
PubMed
Summary
This summary is machine-generated.

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Patients restarting dialysis after a failed kidney transplant have lower survival rates compared to those new to dialysis. Lower serum creatinine levels at the start of second dialysis correlate with better patient survival.

Area of Science:

  • Nephrology
  • Transplantation
  • Renal Replacement Therapy

Context:

  • Limited data exists on patient survival after failed kidney transplants and subsequent dialysis.
  • This study retrospectively analyzed 36 patients who returned to dialysis post-transplant failure.

Purpose:

  • To investigate patient survival and prognostic factors for individuals undergoing dialysis after a failed renal transplant.

Summary:

  • Actuarial survival rates for patients on dialysis after a failed transplant (D2) were 78%, 74%, 69%, and 41% at 1, 2, 3, and 5 years, respectively.
  • These rates were lower than patients starting dialysis without prior transplant history (91%, 85%, 79%, 64% at 1, 2, 3, and 5 years).
  • Lower serum creatinine (<900 µmol/L) at the start of D2 was associated with significantly better 1-year survival (85% vs. 52%).

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Impact:

  • Findings highlight a survival disadvantage for patients returning to dialysis after transplant failure.
  • Serum creatinine levels may serve as a prognostic indicator for this patient group.
  • Informs clinical management and patient counseling regarding outcomes on dialysis post-transplant.