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Delayed CSF seeding of benign oligodendroglioma
S E Natelson1, M L Dyer, D L Harp
1Fort Sanders Regional Medical Center, Knoxville, Tenn.
Southern Medical Journal
|October 1, 1992
Summary
This case study highlights a rare instance of oligodendroglioma recurrence, emphasizing the need for lifelong patient monitoring. Subsequent tumors suggest cerebrospinal fluid (CSF) spread, underscoring long-term surveillance for brain tumor patients.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Oligodendrogliomas are typically slow-growing primary brain tumors.
- Surgical resection is a primary treatment modality for localized oligodendrogliomas.
- Long-term outcomes and recurrence patterns require further investigation.
Observation:
- A 42-year-old male underwent right frontal lobectomy for a benign oligodendroglioma.
- Seventeen years post-surgery, the patient developed a fourth ventricular vermian lesion.
- Histological analysis confirmed the new lesion was identical to the original tumor.
Findings:
- A second, distinct lesion in the left occipital lobe was observed and treated with radiation therapy.
- The identical histology of the subsequent lesions suggests cerebrospinal fluid (CSF) dissemination from the initial tumor.
- This represents a rare case of late-onset, multifocal recurrence attributed to CSF spread.
Implications:
- This case underscores the critical need for indefinite, longitudinal surveillance in patients treated for oligodendroglioma.
- Understanding rare recurrence patterns is vital for optimizing long-term management strategies.
- The findings may inform follow-up protocols for similar brain tumor cases, potentially improving patient outcomes.