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A computerised system of screening for deep venous thrombosis
M D Laverick1, R C McGivern, J G Brown
1Queen's University of Belfast, Department of Orthopaedic Surgery, Musgrave Park Hospital.
Thrombosis Research
|May 1, 1992
Summary
A new computer-controlled strain gauge plethysmography system accurately screens for proximal segment venous thrombosis. This innovative tool demonstrates high sensitivity and negative predictive value, potentially reducing the need for venography in symptomatic patients.
Area of Science:
- Vascular Medicine
- Medical Imaging
- Biomedical Engineering
Background:
- Deep vein thrombosis (DVT) is a significant clinical concern, particularly in the proximal segments.
- Accurate and non-invasive screening methods are crucial for timely diagnosis and treatment.
- Ascending venography, while definitive, is invasive and resource-intensive.
Purpose of the Study:
- To develop and evaluate a computer-controlled strain gauge plethysmography system.
- To assess its accuracy as a screening tool for proximal segment venous thrombosis.
- To determine its potential to optimize the use of ascending venography.
Main Methods:
- Development of a computer-controlled strain gauge plethysmography system.
- Evaluation in 171 limbs of 163 symptomatic patients.
- Comparison of results with ascending venography.
Main Results:
- The system identified 20 out of 20 occlusive proximal segment thrombi.
- One non-occlusive thrombus was incorrectly screened as normal.
- Overall sensitivity was 95.2%, specificity 80%, and negative predictive value 99.0%.
Conclusions:
- Computer-controlled strain gauge plethysmography is an accurate screening tool for proximal segment venous thrombosis.
- The system is simple to use and well-tolerated by patients.
- It may allow for more selective application of venography in symptomatic post-operative limbs.