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[Lumbar disk prolapse treated with chymopapain]
N J Brautaset1, S Hemminghytt, O A Henriksen
1Nevrologisk avdeling, Regionsykehuset i Trondheim.
Summary
Chymopapain injections effectively treated sciatica in 92% of patients, with 81% returning to work within a year. This minimally invasive procedure offers a viable alternative to surgery for select herniated lumbar disc cases.
Area of Science:
- Neurosurgery
- Pain Management
- Minimally Invasive Procedures
Background:
- Sciatica, often caused by herniated lumbar discs, presents a significant challenge in pain management.
- Surgical interventions carry risks and may not be suitable for all patients.
Purpose of the Study:
- To evaluate the efficacy and safety of chymopapain injections for treating sciatica.
- To assess patient outcomes, including return to work, one year after treatment.
Main Methods:
- A prospective study of 108 consecutive patients with sciatica due to herniated lumbar discs.
- Patients were selected based on strict clinical and radiological criteria.
- Follow-up was conducted for one year post-chymopapain injection.
Main Results:
- 92% of patients (99/108) showed improvement after chymopapain injection.
- 81% of all patients (87/108) returned to full-time work within one year.
- A single serious complication of septicemia and possible discitis occurred, with full recovery after antibiotic treatment.
Conclusions:
- Chymopapain injection is an effective treatment for selected patients with sciatica caused by herniated lumbar discs.
- The procedure demonstrates a high success rate in improving patient function and facilitating return to work.
- Chymopapain injection offers a safe and beneficial alternative to surgery for appropriate candidates.