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[Lumbar disk prolapse treated with chymopapain].

N J Brautaset1, S Hemminghytt, O A Henriksen

  • 1Nevrologisk avdeling, Regionsykehuset i Trondheim.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|August 10, 1992
PubMed
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Chymopapain injections effectively treated sciatica in 92% of patients, with 81% returning to work within a year. This minimally invasive procedure offers a viable alternative to surgery for select herniated lumbar disc cases.

Area of Science:

  • Neurosurgery
  • Pain Management
  • Minimally Invasive Procedures

Background:

  • Sciatica, often caused by herniated lumbar discs, presents a significant challenge in pain management.
  • Surgical interventions carry risks and may not be suitable for all patients.

Purpose of the Study:

  • To evaluate the efficacy and safety of chymopapain injections for treating sciatica.
  • To assess patient outcomes, including return to work, one year after treatment.

Main Methods:

  • A prospective study of 108 consecutive patients with sciatica due to herniated lumbar discs.
  • Patients were selected based on strict clinical and radiological criteria.
  • Follow-up was conducted for one year post-chymopapain injection.

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Main Results:

  • 92% of patients (99/108) showed improvement after chymopapain injection.
  • 81% of all patients (87/108) returned to full-time work within one year.
  • A single serious complication of septicemia and possible discitis occurred, with full recovery after antibiotic treatment.

Conclusions:

  • Chymopapain injection is an effective treatment for selected patients with sciatica caused by herniated lumbar discs.
  • The procedure demonstrates a high success rate in improving patient function and facilitating return to work.
  • Chymopapain injection offers a safe and beneficial alternative to surgery for appropriate candidates.