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Related Concept Videos

Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...

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[The origin and distribution of cartilage canals in the chick embryo].

G Doménech-Ratto1, M Moreno-Cascales, A Ballester-Moreno

  • 1Départment des Sciences Morphologiques, Faculté de Médecine, Université de Murcia, Espagne.

Acta Anatomica
|January 1, 1992
PubMed
Summary

This study details the origin and distribution of cartilage canals in chick embryo femurs and tibias. Findings reveal segmental patterns, atypical canals, and connections with marrow processes.

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Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage
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Area of Science:

  • Developmental biology
  • Histology
  • Embryology

Context:

  • Cartilage canals are vascular channels within cartilage crucial for bone development.
  • Understanding their formation and distribution is key to comprehending endochondral ossification.
  • Chick embryos provide a well-established model for studying skeletal development.

Purpose:

  • To describe the origin and distribution of cartilage canals in chick embryo limb bones.
  • To investigate the patterns of cartilage canal formation and their anatomical relationships.
  • To identify atypical cartilage canals and anastomoses with diaphyseal marrow processes.

Summary:

  • Indian ink was used to visualize and trace cartilage canals in 113 chick embryo femurs and 111 tibias (8-21 days post-incubation).
  • The study describes the precise origin and distribution patterns of these canals within the developing bones.
  • A segmental distribution pattern, atypical canals, and anastomoses between epiphyseal canals and diaphyseal marrow processes were observed.

Impact:

  • Provides foundational knowledge on cartilage canal development in avian skeletal embryogenesis.
  • Offers insights into vascularization patterns during endochondral ossification.
  • Contributes to understanding potential anomalies in bone development and vascular supply.