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The aging brain.

H Brody1

  • 1Department of Anatomical Sciences, State University of New York, Buffalo 14214.

Acta Neurologica Scandinavica. Supplementum
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

As the global elderly population grows, understanding normal nervous system aging is crucial for addressing age-related cognitive decline and diseases like Alzheimer's. This review examines structural changes in the aging brain and the nervous system's adaptive responses.

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Area of Science:

  • Neuroscience
  • Gerontology
  • Pathology

Background:

  • Global increase in elderly population.
  • Associated rise in age-related pathologies.
  • Dementias, particularly Alzheimer's Disease, significantly impact older adults.

Purpose of the Study:

  • To review accepted criteria for changes in the normal aging nervous system.
  • To explore the nervous system's adaptive structural responses to aging.

Main Methods:

  • Literature review of established criteria for neural aging.
  • Analysis of studies on nervous system structural plasticity in aging.

Main Results:

  • Compilation of current understanding of age-related structural changes in the brain.

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  • Identification of potential mechanisms for nervous system adaptation to aging.

    • Conclusions:

    • Understanding normal aging is fundamental to comprehending age-related neurological diseases.
    • The nervous system exhibits adaptive structural alterations in response to aging.