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Updated: Sep 4, 2026

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
Published on: August 14, 2017
A USEFUL PHOTOMETRIC TEST FOR THE DIAGNOSIS OF VON WILLEBRAND'S DISEASE
When small amounts of adenosine diphosphate are added to citrated platelet-rich plasma, the consequent modification of platelets leads to a decrease in optical density. In Von Willebrand's disease the optical density at 610 mmu increases instead of decreasing. This finding is used to study the effects of treatment on this disorder.
When small amounts of adenosine diphosphate are added to citrated platelet-rich plasma, the consequent modification of platelets leads to a decrease in optical density. In Von Willebrand's disease the optical density at 610 mmu increases instead of decreasing. This finding is used to study the effects of treatment on this disorder.

