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Updated: Jul 19, 2026
07:34
FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
A prospective cytogenetic study of 36 cases of DiGeorge syndrome
D I Wilson1, I E Cross, J A Goodship
1Division of Human Genetics, University of Newcastle upon Tyne, U.K.
American Journal of Human Genetics
|November 1, 1992
Abstract:
Cytogenetic analysis was carried out in a prospective series of 36 children with DiGeorge syndrome. High-resolution banding (> 850 bands/haploid set) was achieved in 30 cases. Monosomy 22q11.21-->q11.23 was found in 9 of these 30 cases. In each of these cases monosomy 22q11.21-->q11.23 resulted from an interstitial deletion and not from a translocation. No other chromosome abnormalities were seen.
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