Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Birth weight threshold for postponing preterm birth.

R T DePalma1, K J Leveno, M A Kelly

  • 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.

American Journal of Obstetrics and Gynecology
|October 1, 1992
PubMed
Summary

For preterm births, delaying delivery for infants over 1600 grams may reduce mortality. However, benefits for neonatal morbidity are less clear above 1900 grams.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urine congophilia associated with preeclampsia does not persist 6-months postpartum.

Placenta·2024
Same author

The opportunity cost of arthroplasty training in orthopaedic surgery.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2021
Same author

A unified call to action from Australian nursing and midwifery leaders: ensuring that Black lives matter.

Contemporary nurse·2020
Same author

Quantifying the polygenic contribution to variable expressivity in eleven rare genetic disorders.

Nature communications·2019
Same author

Vitamin D Insufficiency in Patients Undergoing Total Knee Arthroplasty in Ireland.

Irish medical journal·2018
Same author

Teaching Musculoskeletal Medicine to Undergraduate Students in a Simulated Environment.

Irish medical journal·2018

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Perinatal Research

Background:

  • Preterm birth remains a leading cause of neonatal morbidity and mortality.
  • Identifying optimal intervention thresholds for preterm deliveries is crucial for improving neonatal outcomes.
  • Spontaneous preterm labor and preterm rupture of membranes are common indications for preterm birth.

Purpose of the Study:

  • To determine the birth weight threshold for potentially improving neonatal outcomes in pregnancies complicated by spontaneous preterm labor or preterm rupture of membranes.
  • To evaluate the impact of obstetric interventions aimed at delaying delivery based on birth weight.
  • To inform clinical decision-making regarding the management of preterm pregnancies.

Main Methods:

  • A retrospective study of 1147 singleton infants with birth weights between 1000 and 2499 gm.

Related Experiment Videos

  • Infants were selected based on spontaneous preterm labor or preterm rupture of membranes as the sole complication.
  • Mantel-Haenszel chi 2 statistic was used to analyze trends in neonatal mortality and morbidity.

    • Main Results:

    • A significant birth weight threshold of 1600 gm was identified for reducing neonatal mortality (p < 0.001).
    • The threshold for neonatal morbidity was found to be between 1600 and 1900 gm (p < 0.008).
    • Infants exceeding 1900 gm showed minimal apparent benefits from aggressive obstetric interventions to delay delivery.

    Conclusions:

    • Aggressive obstetric interventions to delay preterm birth may not offer significant benefits for infants weighing over 1900 gm.
    • The findings suggest a nuanced approach to managing preterm labor, considering birth weight thresholds.
    • Further research may explore specific interventions and their efficacy at different birth weight strata.