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Radial Mobility and Cytotoxic Function of Retroviral Replicating Vector Transduced, Non-adherent Alloresponsive T Lymphocytes
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Published on: February 11, 2015

HOMOGRAFT TARGET CELLS: SPECIFIC DESTRUCTION IN VITRO BY CONTACT INTERACTION WITH IMMUNE MACROPHAGES

G A GRANGER, R S WEISER

    Science (New York, N.Y.)
    |September 25, 1964
    PubMed

    Specific adherence and mutual immunologic destruction occurred after contact in vitro of immune peritoneal macrophages from C57BI/6K mice with homograft target cells from A/Jax mice. Cell destruction apparently resulted from a nonphagocytic mechanism involving cell contact rather than humoral antibody. Cell destruction was determined by a plaque technique with either immunecells or target cells as monolayers.

    Keywords:
    EXPERIMENTAL LAB STUDYFIBROBLASTSL CELLSMACROPHAGESMICEPERITONEUMSARCOMA, EXPERIMENTALTISSUE CULTURETRANSPLANTATIONTRANSPLANTATION IMMUNOLOGY

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