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CDw 60 antibodies bind to acetylated forms of ganglioside GD3

B Kniep1, J Peter-Katalinić, W Flegel

  • 1GBF-Gesellschaft für Biotechnologische Forschung mbH, Braunschweig, FRG.

Biochemical and Biophysical Research Communications
|September 30, 1992
PubMed

Four monoclonal antibodies, M-T21, M-T32, M-T41 and UM4D4, which belong to the new CDw 60 cluster of antibodies specific for a subpopulation of human T-lymphocytes, were found to bind mainly to acetylated forms of ganglioside GD3. After O-deacetylation of the antigen, binding was reduced ("M-T"-antibodies) or abolished (UM4D4).

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