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[Coronary arteriosclerosis and risk factors in coronary heart disease (author's transl)]
Insights
This study analyzed clinical risk factors for coronary heart disease and coronary arteriosclerosis. Findings suggest additional morphological criteria are needed to fully explain heart attacks not involving major coronary arteries.
Area of Science:
- Cardiology
- Pathology
- Biostatistics
Abstract:
A large number of cases were tested for the relevance of clinical risk factors in coronary heart disease with regard to coronary arteriosclerosis (atheroma, fibrosis; five different locations). The method applied was VARIMAX-rotated factor analysis. The resulting factors were interpreted as the multiple variables structures which are in different relationships to the risk criterion, coronary heart disease, and morphological vascular diagnosis of the coronary arteries. The importance of the known risk of the vascular diagnosis was estimated and the reterance of the clinically influencing criterion was discussed. It appears that in spite of limited methodology additional morphological criteria are required in order to be able to explain heart infarction which does not involve the epicardial branches of the coronary vascular system.