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ARTIFICIAL CARDIAC PACEMAKERS
Insights
Artificial cardiac pacemakers effectively treated patients with complete heart block and Stokes-Adams disease. Eight of nine patients experienced improved physical activity and freedom from seizures after pacemaker implantation.
Area of Science:
- Cardiology
- Biomedical Engineering
Background:
- Complete heart block and Stokes-Adams disease significantly impair patients, often rendering them bedridden.
- Medical treatments for these conditions can be insufficient, necessitating alternative interventions.
Purpose of the Study:
- To evaluate the efficacy and safety of subcutaneously implanted, fixed-rate artificial cardiac pacemakers in patients with complete heart block and Stokes-Adams disease.
Main Methods:
- Nine patients with complete heart block and Stokes-Adams disease, refractory to medical treatment, underwent implantation of fixed-rate artificial cardiac pacemakers.
- Pacemaker function and patient outcomes, including seizure frequency and physical activity, were monitored.
Main Results:
- Eight out of nine patients showed adequate stimulation and significant improvement in physical activity.
- Patients were free from seizures post-implantation, with a fixed rate of 60-65 beats per minute proving adequate.
- One patient experienced a fatal outcome due to uremia one month post-operation.
Conclusions:
- Subcutaneously implanted artificial cardiac pacemakers offer a satisfactory treatment for selected patients with complete heart block and Stokes-Adams disease.
- The potential for mechanical failure necessitates limiting pacemaker use to incapacitated patients unresponsive to medical management.
Abstract:
Nine patients with complete heart block and Stokes-Adams disease were treated with subcutaneously implanted, fixed-rate, artificial cardiac pacemakers. All of these patients were refractory to medical treatment and confined to bed by the frequency of their attacks. One patient died in uremia one month after operation; in the remaining eight, the implanted pacemakers are providing adequate stimulation at present. These patients are free of seizures and show an improvement in the amount of their physical activity. A fixed rate of 60 to 65 per minute was adequate in all cases. The results of our clinical experience with cardiac pacemakers is satisfactory, but the possibility of mechanical failure limits their use to situations in which the patient is incapacitated despite medical treatment.
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The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...

