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Updated: Aug 25, 2026

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Uncontrolled epilepsy in children

W T Blume1

  • 1Epilepsy Unit, University Hospital, University of Western Ontario, London, Canada.

Epilepsy Research. Supplement
|January 1, 1992
PubMed

Insights

Intractable seizures require careful management, considering seizure frequency, patient lifestyle, and potential surgical benefits. Surgery

Area of Science:

  • Neurology
  • Neurosurgery

Background:

  • Intractable seizures are defined by persistent, unacceptable seizure activity despite medical and social management, or seizure control at the cost of medication toxicity.
  • The determination of unacceptable seizure levels is influenced by seizure type, patient lifestyle, and the consequences of uncontrolled epilepsy.

Purpose of the Study:

  • To define intractable seizures and outline the factors influencing their management.
  • To highlight the potential role and future improvements in surgical interventions for intractable epilepsy.

Main Methods:

  • This abstract does not detail specific methods but discusses the conceptual framework for defining and managing intractable seizures.
  • It emphasizes the need for objective evaluation of surgical outcomes.

Main Results:

  • The abstract does not present specific results but establishes criteria for defining intractable seizures.
  • It posits that the value of epilepsy surgery will increase with improved patient selection and diagnostic accuracy.

Conclusions:

  • Accurate selection of surgical candidates and sites, along with precise identification of diagnostic tests, will enhance the efficacy of surgical interventions for intractable epilepsy.
  • Objective evaluation of surgical outcomes is crucial for understanding its true value.

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