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Updated: Aug 2, 2026

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
Published on: January 20, 2010
[Tracheal prosthesis]
Abstract:
A prosthesis of the authors' design with various connective elements of knitted Lavsan fabric was tested in experiments on 43 mongrel dogs. Clinical, radiological, radiospirographic, and morphological studies showed that the optimal prosthesis is that in which the connective elements are made of knitted Lavsan fabrics with an average stitch size of 20-23. Granulation tissue grows through the prosthesis which is fastened well to the connective-tissue cuff forming around it. The trachea replaced by the prosthesis ensures adequate gas exchange and lung functioning, causes no essential disorders of pulmonary volumes, ventilation and perfusion of the right and left lungs.
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