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Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing
Published on: September 25, 2011
The expression of 5T4 antigen in colorectal and gastric carcinoma
T Starzynska1, V Rahi, P L Stern
1Department of Gastroenterology, Medical Pomeranian Academy, Szczecin, Poland.
British Journal of Cancer
|November 1, 1992
Abstract:
The expression of 5T4, an oncotrophoblast cell surface antigen was examined in 72 colorectal and 27 gastric carcinomas, with immunoperoxidase technique, on frozen sections. Highly significant association was found between 5T4 expression in the malignant cells and metastatic spread. The results suggest that the appearance of 5T4 molecules in cancer cells reflects a change which may contribute to the development of metastatic potential.
