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Updated: Aug 15, 2026

In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
Neuroradiology of intracranial infection
1Department of Radiology and Neurology, Indiana University School of Medicine, Indianapolis.
Abstract:
The ability to detect and differentiate intracranial infection has markedly improved, first with the introduction of computed tomography and, more recently, with magnetic resonance. Enhanced magnetic resonance imaging is the procedure of choice in the evaluation of nearly all intracranial infections. The sensitivity of MR to foci of increased water content, seen in most parenchymal infections, the lack of bone artifact, and the multiplanar capability of MR have led to this preeminence. Computed tomography remains useful primarily in those infections associated with intracranial calcification, such as TORCH syndrome. This article summarizes the most recent CT and MR findings of infection involving the meninges and brain parenchyma.
Insights
Magnetic resonance imaging (MRI) is now the preferred method for detecting intracranial infections due to its superior sensitivity and multiplanar capabilities. Computed tomography (CT) remains valuable for specific calcified infections.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Intracranial infections pose significant diagnostic challenges.
- Advancements in imaging have improved detection and differentiation.
- Computed tomography (CT) and magnetic resonance imaging (MR) are key neuroimaging modalities.
Purpose of the Study:
- To review recent findings in CT and MR imaging of intracranial infections.
- To highlight the role of enhanced MR imaging in evaluating these conditions.
- To compare the utility of CT and MR in specific infectious scenarios.
Main Methods:
- Review of current literature on CT and MR imaging findings in intracranial infections.
- Emphasis on enhanced magnetic resonance imaging techniques.
- Discussion of CT's role in calcified infections like TORCH syndrome.
Main Results:
- Enhanced MR imaging is the primary diagnostic tool for most intracranial infections.
- MR's sensitivity to water content and multiplanar views are advantageous.
- CT is particularly useful for infections with intracranial calcifications.
Conclusions:
- Enhanced MR imaging offers superior evaluation for the majority of intracranial infections.
- CT remains essential for diagnosing infections characterized by calcification.
- Accurate interpretation of CT and MR findings is crucial for effective management.
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