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Frequency of HLA-DPB1 alleles in multiple sclerosis patients from Northern Ireland
D Middleton1, D A Savage, C Cullen
1Northern Ireland Tissue Typing Service, City Hospital, Belfast, UK.
Abstract:
Using sequence-specific oligonucleotide probes, no altered distribution in the frequency of HLA-DPB1 alleles was found in multiple sclerosis patients from Northern Ireland. Although present in the controls, linkage disequilibrium between HLA-DPB1*0101 and HLA-DR17 was not found in multiple sclerosis patients.