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Updated: Aug 15, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
Published on: October 22, 2012
[Seasonal changes in amine-containing structures of the thymus during the 1st hour of antigen effects]
Abstract:
Using luminescent-histochemical and microspectrofluorimetric techniques, the combination of early visual and quantitative changes of catecholamine and serotonin content in biogenic amine-containing thymus structures during the first hour contact of the body with the T-dependent antigen (sheep red blood cells) has been studied. The experiments were made on 60 male rats of Wistar-2 line, white laboratory rats in spring and autumn. The degree and direction of the changes were found to depend on the baseline neuromediator levels.
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