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Portal hypertensive gastropathy.

D R Triger1

  • 1University of Sheffield Medical School, UK.

Bailliere'S Clinical Gastroenterology
|September 1, 1992
PubMed
Summary

Portal hypertensive gastropathy is a significant cause of gastrointestinal bleeding in patients with portal hypertension. Propranolol is effective in controlling hemorrhage, making it the preferred treatment.

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Area of Science:

  • Gastroenterology
  • Hepatology
  • Internal Medicine

Background:

  • Portal hypertensive gastropathy (PHG) is an increasingly recognized cause of gastrointestinal bleeding in patients with portal hypertension.
  • It becomes more frequent with longer survival after treatment for bleeding esophageal varices.

Purpose of the Study:

  • To review the clinical significance, pathogenesis, and management of portal hypertensive gastropathy.
  • To differentiate PHG from other gastrointestinal disorders.

Main Methods:

  • Review of clinical evidence regarding PHG.
  • Discussion of endoscopic and histological characteristics.
  • Analysis of treatment options and their efficacy.

Main Results:

  • PHG is a major source of bleeding, especially after variceal treatment.
  • Pathogenesis involves venous congestion and arterial abnormalities, but is not fully understood.
  • Portocaval shunt surgery cures PHG; propranolol is highly effective for hemorrhage control.

Conclusions:

  • Portal hypertensive gastropathy is a key cause of GI bleeding in portal hypertension.
  • Propranolol is the current treatment of choice for managing hemorrhage from PHG.
  • Further research is needed to clarify the exact pathogenesis and explore other treatment options.

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