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Related Experiment Videos

Heparin and infusion phlebitis: a prospective study.

J A Nieto-Rodriguez1, M A Garcìa-Martìn, M D Barreda-Hernandez

  • 1Internal Medicine Department, Hospital Virgen de la Luz, Cuenca, Spain.

The Annals of Pharmacotherapy
|October 1, 1992
PubMed
Summary

Adding heparin sodium to peripheral IV fluids significantly reduces catheter-related problems like phlebitis and obstruction. This intervention also extends the functional lifespan of intravenous catheters in patients.

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Area of Science:

  • Medical devices
  • Pharmacology
  • Nursing interventions

Background:

  • Peripheral intravenous catheters are essential for patient care but prone to complications.
  • Catheter-related problems, including phlebitis, obstruction, and extravasation, can lead to premature removal and increased healthcare costs.

Purpose of the Study:

  • To evaluate the efficacy of heparin sodium in preventing local catheter-related issues.
  • To determine if heparin sodium extends the indwelling time of peripheral intravenous catheters.

Main Methods:

  • Prospective, double-blind, placebo-controlled study.
  • Inclusion of 81 acute patients with forearm venous catheters.
  • Administration of infusion fluids with either heparin sodium (1 unit/mL) or a placebo (NaCl 0.9%).

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Main Results:

  • The heparin group experienced significantly fewer local catheter-related problems (34.3%) compared to the placebo group (61.5%).
  • Mean catheter dwell time was extended in the heparin group (98.9 hours) versus the placebo group (66.2 hours).
  • Heparin demonstrated effectiveness in preventing non-inflammatory issues and delaying phlebitis onset.

Conclusions:

  • Heparin sodium, at a concentration of 1 unit/mL in infusion fluids, effectively reduces intravenous catheter-related complications.
  • The addition of heparin sodium prolongs the useful life of peripheral intravenous catheters.