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Dissociation of neurocognitive deficits in a monozygotic twin pair concordant for schizophrenia
R Condray1, S R Steinhauer, D P van Kammen
1Department of Veterans Affairs Medical Center, Pittsburgh, PA 15206.
Abstract:
Cognitive impairment varies markedly among schizophrenic individuals, although the reason for this is unknown. A monozygotic twin pair concordant for schizophrenia was evaluated using electrophysiological and neurobehavioral measures. Each twin showed a distinctive pattern of deficits; furthermore, clinical course and electrophysiological activity were not consonant with social and neurobehavioral functioning. Results suggest complex interrelationships between neurocognitive functioning and clinical presentation in schizophrenia.
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