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Related Experiment Videos

Randomized trial of loop ileostomy in restorative proctocolectomy.

S P Grobler1, K B Hosie, M R Keighley

  • 1University Department of Surgery, Queen Elizabeth Medical Centre, Birmingham, UK.

The British Journal of Surgery
|September 1, 1992
PubMed
Summary

Avoiding a loop ileostomy after restorative proctocolectomy is safe and reduces hospital stay. Loop ileostomies lead to frequent complications, suggesting they are unnecessary for patients with a secure ileoanal anastomosis.

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Area of Science:

  • Colorectal Surgery
  • Surgical Outcomes
  • Gastroenterology

Background:

  • Restorative proctocolectomy is a surgical procedure for ulcerative colitis and familial adenomatous polyposis.
  • A loop ileostomy is sometimes used to protect the ileoanal anastomosis after this surgery.
  • The necessity and impact of loop ileostomies on patient outcomes require further investigation.

Purpose of the Study:

  • To evaluate the role and complications of a loop ileostomy in patients undergoing totally stapled restorative proctocolectomy.
  • To compare outcomes between patients with and without a protective loop ileostomy.

Main Methods:

  • A randomized controlled trial was conducted.
  • Eligible patients (n=45) without corticosteroid use and with a watertight pouch and intact ileoanal anastomosis were randomized to receive a loop ileostomy (n=23) or no ileostomy (n=22).

Related Experiment Videos

  • Outcomes including anastomotic leaks, stenosis, sepsis, obstruction, pouchitis, ileostomy complications, and hospital stay were assessed.
  • Main Results:

    • No deaths occurred; anastomotic leaks were similar in both groups (one in each).
    • Ileoanal stenosis was more frequent in the ileostomy group (5 vs. 1).
    • Ileostomy-related complications occurred in 52% of patients with an ileostomy, and the median hospital stay was significantly longer (23 days vs. 13 days, P < 0.001).

    Conclusions:

    • Avoiding a protective loop ileostomy in totally stapled restorative proctocolectomy is associated with a low risk of pelvic sepsis.
    • Loop ileostomy is linked to a high incidence of complications and prolonged hospital stay.
    • Routine use of loop ileostomy may not be necessary in selected patients undergoing restorative proctocolectomy.