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Related Experiment Videos

CMAP: contig mapping and analysis package, a relational database for chromosome reconstruction.

A J Cuticchia1, J Arnold, H Brody

  • 1Department of Genetics, University of Georgia, Athens 30602.

Computer Applications in the Biosciences : CABIOS
|October 1, 1992
PubMed
Summary

The Contig Mapping and Analysis Package (CMAP) organizes DNA fragment data into a physical map for reverse genetics. This user-friendly software facilitates DNA fragment analysis and physical map creation, aiding genetic research.

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Human mapping databases.

Current protocols in human genetics·2008

Area of Science:

  • Genomics
  • Bioinformatics
  • Molecular Biology

Background:

  • Reverse genetics requires organizing DNA fragment information.
  • Physical maps are crucial for understanding genome organization.

Purpose of the Study:

  • To develop a software package for creating and managing physical maps of DNA fragments.
  • To provide a foundation for reverse genetics research through organized data storage and retrieval.

Main Methods:

  • Developed the Contig Mapping and Analysis Package (CMAP) software.
  • Implemented a database for storing descriptive and experimental DNA fragment data.
  • Designed a user interface with error-checking protocols and menu-driven query options.
  • Utilized dynamic SQL for flexible data querying.

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Main Results:

  • CMAP organizes DNA fragment information into a physical map.
  • Users can store descriptive and experimental data for DNA fragments.
  • The software allows for updating the physical map and retrieving fragment information.
  • An intuitive interface minimizes the learning curve for database usage.

Conclusions:

  • CMAP provides a robust database for physical map production and storage.
  • The software serves as a foundational tool for a physical mapping workstation.
  • CMAP facilitates reverse genetics by organizing genomic data.