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Related Experiment Videos

Does cancer survival differ for older patients?

A K Kant1, C Glover, J Horm

  • 1Division of Mathematics and Natural Sciences, Queens College, City University of New York, Flushing 11367-0904.

Cancer
|December 1, 1992
PubMed
Summary

Older cancer patients generally have lower survival rates, with advanced disease more common in older women. Racial disparities in survival exist, but age-related trends were similar across races.

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Area of Science:

  • Oncology
  • Epidemiology
  • Cancer Research

Background:

  • Age is a significant factor in cancer patient outcomes.
  • Understanding age-related survival trends is crucial for cancer care.
  • Previous studies have indicated varying survival rates across different age groups.

Purpose of the Study:

  • To examine the relationship between patient age and 5-year relative survival rates for major fatal cancer sites.
  • To investigate if age-related survival differences are influenced by cancer stage at diagnosis.
  • To compare age-survival trends between different racial groups.

Main Methods:

  • Analysis of data from 127,554 patients diagnosed between 1978 and 1982.
  • Inclusion of data from four Surveillance, Epidemiology and End Results (SEER) program areas.

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  • Examination of overall and stage-stratified relative survival rates stratified by age.

    • Main Results:

    • Declining 5-year relative survival rates with increasing patient age for lung, prostate, pancreas, bladder, oral cavity, uterus, cervix, ovary, and large bowel cancers.
    • In men, age-related survival decline was not linked to diagnosis stage; in women, older age correlated with more advanced disease for most sites.
    • Black patients had lower overall survival than white patients, but age-survival and age-stage trends were consistent across racial groups.

    Conclusions:

    • Advanced age is associated with poorer survival outcomes for numerous common cancers.
    • The impact of age on cancer stage at diagnosis differs between men and women.
    • While racial disparities in cancer survival exist, age-related prognostic factors appear consistent across races.