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[A prospective study on the relationship between abnormal pregnant outcome and Toxoplasma gondii infection]
1Department of Epidemiology, Shandong Medical University, Jinan.
2821 pregnant women were divided into three groups according to the phenomena of Toxoplasma gondii infection, and the pregnancy outcomes were followed up. Results show that the total incidence rates of spontaneous abortion, premature birth, still birth and congenital defects are 0.67%, 3.47%, 0.85% and 0.96% respectively. These four rates in the group serodiagnosed as recently or actively infected are significantly higher than that diagnosed as no evidence of infections and the relative risk estimates (ORmh) are 7.38, 3.52, 8.68 and 9.44 respectively. Differences of the four rates between group diagnosed as past infection and that of no evidence of infection are not statistically significant. Analysis between the time of serodiagnosis and the incidence of abnormal pregnant outcome shows that congenital defects is statistically related with infection in the first trimester of gestation.
2821 pregnant women were divided into three groups according to the phenomena of Toxoplasma gondii infection, and the pregnancy outcomes were followed up. Results show that the total incidence rates of spontaneous abortion, premature birth, still birth and congenital defects are 0.67%, 3.47%, 0.85% and 0.96% respectively. These four rates in the group serodiagnosed as recently or actively infected are significantly higher than that diagnosed as no evidence of infections and the relative risk estimates (ORmh) are 7.38, 3.52, 8.68 and 9.44 respectively. Differences of the four rates between group diagnosed as past infection and that of no evidence of infection are not statistically significant. Analysis between the time of serodiagnosis and the incidence of abnormal pregnant outcome shows that congenital defects is statistically related with infection in the first trimester of gestation.