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Risk factors for HIV infection in homosexual men: the Cleveland men's study of risks in a low-prevalence area
1Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106-4984.
Insights
Human immunodeficiency virus (HIV) infection risk factors were studied in homosexual men. Intravenous drug use and receptive anal-genital sex were identified as key predictors of HIV seropositivity.
Area of Science:
- Epidemiology
- Public Health
- Virology
Background:
- Homosexual men are a key population for human immunodeficiency virus (HIV) research.
- Understanding risk factors for HIV infection is crucial for prevention strategies.
Purpose of the Study:
- To identify behaviors and characteristics associated with HIV seropositivity among homosexual men in Cleveland.
- To determine independent predictors of HIV infection in this demographic.
Main Methods:
- A cross-sectional study involving 301 homosexual men in the Cleveland metropolitan area.
- Data collection via detailed questionnaires on lifestyle and medical history.
- Serological testing for antibodies to human immunodeficiency virus (HIV).
Main Results:
- 18.6% of participants (56 out of 301) were seropositive for HIV.
- Univariate analysis indicated associations between seropositivity and age, drug use, and specific sexual practices.
- Multiple logistic regression identified intravenous drug use and receptive anal-genital sex as independent predictors.
Conclusions:
- Intravenous drug use and receptive anal-genital sex are significant independent risk factors for HIV infection in homosexual men.
- These findings can inform targeted HIV prevention and intervention programs.
Abstract:
Detailed questionnaires concerning alcohol and drug use, sexual practices, and medical history were completed by 301 homosexual men living in the Cleveland metropolitan area. Their sera were subsequently tested for antibodies to the human immunodeficiency virus. Fifty-six (18.6%) were seropositive. In a univariate analysis, age, drug use, and four specific sexual practices were associated with seropositivity. In a multiple logistic regression analysis, intravenous drug use and receptive anal-genital sex remained independent predictors of seropositivity.