Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evaluating agreement between two methods for measuring the same quantity: a response.

J Lee1

  • 1Department of Community, Occupational and Family Medicine, National University of Singapore.

Computers in Biology and Medicine
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional analysis of Box II mutations in yeast site-specific recombinases Flp and R. Significance of amino acid conservation within the Int family and the yeast sub-family.

Journal of molecular biology·1992
Same author

Fluorescence study of the ligand stereospecificity for binding to lumazine protein.

European journal of biochemistry·1992
Same author

Reduction of postoperative adhesions in strabismus surgery.

Korean journal of ophthalmology : KJO·1992
Same author

The Red Cross and CDC's natural-disaster surveillance system.

American journal of public health·1992
Same author

Cumulative logit modelling for ordinal response variables: applications to biomedical research.

Computer applications in the biosciences : CABIOS·1992
Same author

The sagittal ramus osteotomy. Stability of fixation with internal miniplates.

International journal of oral and maxillofacial surgery·1992
Same journal

sEEGnal: an automated EEG preprocessing pipeline evaluated against expert-driven preprocessing.

Computers in biology and medicine·2026
Same journal

Corrigendum to "Integrating experimental biology, computational methods, and artificial Intelligence in anticancer drug discovery: Bridging the translational Gap" [Comput. Biol. Med. 213 (2026) 111832].

Computers in biology and medicine·2026
Same journal

Organ dose optimization for a point-of-care forearm X-ray photon-counting CT.

Computers in biology and medicine·2026
Same journal

Physics-guided transformation of breathomic feature spaces into disease-specific representations for respiratory disease classification.

Computers in biology and medicine·2026
Same journal

An AI-driven deep learning pipeline for taxonomic classification and biodiversity assessment of deep-sea environmental DNA.

Computers in biology and medicine·2026
Same journal

Rapid personalisation of cardiovascular models using invasively measured right ventricular pressure.

Computers in biology and medicine·2026
See all related articles

This study evaluates two statistical indices for method agreement, finding both the intraclass correlation and limits of agreement have limitations. Careful consideration of specific situations is needed for accurate method comparison.

Area of Science:

  • Biostatistics
  • Medical Statistics
  • Clinical Chemistry

Background:

  • Method comparison studies assess agreement between new and established measurement techniques.
  • Absolute method agreement is crucial for reliable diagnostic and clinical decisions.
  • Existing statistical indices for agreement have limitations.

Purpose of the Study:

  • To critically evaluate two common statistical indices for absolute method agreement: intraclass correlation and limits of agreement.
  • To identify deficiencies in each index when quantifying agreement between measurement methods.

Main Methods:

  • Scrutiny of the intraclass correlation coefficient (ICC) for method agreement.
  • Analysis of the 'limits of agreement' (LoA) method for assessing agreement.

Related Experiment Videos

  • Comparative evaluation of the strengths and weaknesses of ICC and LoA in method comparison studies.

    • Main Results:

    • Neither the intraclass correlation nor the limits of agreement are without statistical deficiencies for measuring absolute method agreement.
    • Both indices demonstrate limitations in fully capturing the nuances of method agreement.
    • Specific contexts may favor one index over the other.

    Conclusions:

    • The intraclass correlation and limits of agreement, while widely used, require careful application in method comparison studies.
    • Understanding the inherent limitations of each index is essential for accurate interpretation of method agreement.
    • Context-specific application allows each index to play a valuable role in quantitative method agreement assessment.