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Evaluation of clinical data in bladder cancer immunotherapy with Connaught BCG (ImmuCyst)

L Barreto1, Z Csizer, J D Sparkes

  • 1Connaught Laboratories Limited, Willowdale, Ontario, Canada.

Developments in Biological Standardization
|January 1, 1992
PubMed

Treatment of superficial bladder carcinoma in situ with Connaught BCG (ImmuCyst) significantly increased complete response rate and extended the disease-free interval when compared with Doxorubicin (DOX) chemotherapy. In 54 patients treated with ImmuCyst, 74% showed complete response compared with 42% of 60 patients treated with DOX. The median disease-free time was 48.2 months for BCG and 5.9 months for DOX treatment. Types and severity of adverse reactions were similar for both treatments and within tolerable ranges.

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