Vitamin C and serendipity, fifty years ago

Studies on pyrazinoylguanidine: a novel antihypertensive, hypoglycemic and lipolytic drug intended for adjunctive use in hypertensive patients with type 2 diabetes mellitus.

Toxicology·2000

Studies on pyrazinoylguanidine. 7. Effects of single oral doses in normal human subjects.

Pharmacology·1999

Pyrazinoylguanidine in end-stage renal disease: a prospective, placebo-controlled pilot study.

Pharmacology·1998

Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats.

Pharmacology·1997

Studies on pyrazinoylguanidine. 6. Prevention of cataracts in STZ-diabetic rats.

Pharmacology·1997

Studies on pyrazinoylguanidine. 3. Downregulation of lipolysis in isolated adipocytes.

Pharmacology·1996

Explainable Plasma Proteomics-Based Machine Learning for Osteoporosis Diagnosis, Prognosis, and Protein Biomarker Discovery in the UK Biobank.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Identification of Ferro-Aging-Related Biomarkers for Ulcerative Colitis Through Integrated Machine Learning, Single-Cell Analysis, and Spatial Transcriptomics.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Explainable Deep Learning of Transcriptomes Prioritizes Candidate Biomarkers With Preferential Performance in Gastric Cardia Cancer Cohorts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Expression of Active Apurinic Apyrimidinic Endodeoxyribonuclease 1 in Human Platelets.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Analysis of the factors affecting the quality of life in patients with pituitary adenomas before and after endoscopic transsphenoidal surgery.

Frontiers in endocrinology·2026

Persistent Redox Imbalance in Post-COVID-19 Syndrome: Lipid Peroxidation, Antioxidant Enzyme Depletion, and Reduced Nitric Oxide Availability in an Amazonian Population.

Antioxidants (Basel, Switzerland)·2026

A Purified Lycii Fructus Polysaccharide Fraction Extends Healthspan in Caenorhabditis elegans with an ATFS-1/UBL-5-Associated Mitochondrial Unfolded Protein Response.

Antioxidants (Basel, Switzerland)·2026

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Vitamin C and serendipity, fifty years ago

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Studies on pyrazinoylguanidine: a novel antihypertensive, hypoglycemic and lipolytic drug intended for adjunctive use in hypertensive patients with type 2 diabetes mellitus.

Studies on pyrazinoylguanidine. 7. Effects of single oral doses in normal human subjects.

Pyrazinoylguanidine in end-stage renal disease: a prospective, placebo-controlled pilot study.

Studies on pyrazinoylguanidine. 5. Temporal effects over 24 weeks demonstrating attenuation of diabetic nephropathy in STZ-diabetic rats.

Studies on pyrazinoylguanidine. 6. Prevention of cataracts in STZ-diabetic rats.

Studies on pyrazinoylguanidine. 3. Downregulation of lipolysis in isolated adipocytes.

Explainable Plasma Proteomics-Based Machine Learning for Osteoporosis Diagnosis, Prognosis, and Protein Biomarker Discovery in the UK Biobank.

Identification of Ferro-Aging-Related Biomarkers for Ulcerative Colitis Through Integrated Machine Learning, Single-Cell Analysis, and Spatial Transcriptomics.

Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists.

Explainable Deep Learning of Transcriptomes Prioritizes Candidate Biomarkers With Preferential Performance in Gastric Cardia Cancer Cohorts.

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development.

Expression of Active Apurinic Apyrimidinic Endodeoxyribonuclease 1 in Human Platelets.

Analysis of the factors affecting the quality of life in patients with pituitary adenomas before and after endoscopic transsphenoidal surgery.

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Low cardiovascular risk in early midlife and quality of life in old age: a life-long follow-up study in men.

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Persistent Redox Imbalance in Post-COVID-19 Syndrome: Lipid Peroxidation, Antioxidant Enzyme Depletion, and Reduced Nitric Oxide Availability in an Amazonian Population.

A Purified Lycii Fructus Polysaccharide Fraction Extends Healthspan in Caenorhabditis elegans with an ATFS-1/UBL-5-Associated Mitochondrial Unfolded Protein Response.

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Vitamin C and serendipity, fifty years ago

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