Related Experiment Video
Updated: Jun 14, 2026

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
Published on: July 18, 2013
LINKAGE IN CONTROL OF ALLOTYPIC SPECIFICITIES ON TWO DIFFERENT GAMMA-G-IMMUNOGLOBULINS
Allotypic specificities were identified on two different myeloma proteins and the corresponding normal gammaG-immunoglobulins of BALB/c mice. When the sera of F(2) progeny from a cross between BALB/c mice having the a1 allotype and AL mice having the a4 allotype were tested for these specificities, it was found that the two allotypic specificities of the BALB/c mice were either both present (87 mice) or both absent (36 mice), an indication of linkage in their genetic control.
Allotypic specificities were identified on two different myeloma proteins and the corresponding normal gammaG-immunoglobulins of BALB/c mice. When the sera of F(2) progeny from a cross between BALB/c mice having the a1 allotype and AL mice having the a4 allotype were tested for these specificities, it was found that the two allotypic specificities of the BALB/c mice were either both present (87 mice) or both absent (36 mice), an indication of linkage in their genetic control.
More Related Videos
11:10Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
Published on: June 29, 2016
06:51Dual-modality Molecular Cartography: Integrating Multiplex mRNA Detection with Protein Imaging Mass Cytometry
Published on: November 14, 2025
Related Concept Videos
Cell-mediated Immune Responses
Immunoglobulin-like Cell Adhesion Molecules
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Diversity of Antigen Receptors
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
T Cell Activation and Clonal Selection
Naive T cells that have not yet encountered an antigen express two primary CD...
B Cell Activation and Differentiation
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...