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Hand angiography and Raynaud's syndrome
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|July 1, 1977
Summary
Magnification hand angiography effectively diagnoses Raynaud's syndrome by assessing cold-induced vasospasm. Reserpine improved vasospasm, correlating with better long-term vasodilator therapy outcomes.
Area of Science:
- Vascular Medicine
- Radiology
- Pharmacology
Background:
- Raynaud's syndrome involves exaggerated arterial vasospasm.
- Organic obstructive disease often coexists.
- Diagnostic and therapeutic prediction methods are needed.
Purpose of the Study:
- To evaluate magnification hand angiography with cold exposure and reserpine for Raynaud's syndrome.
- To assess the diagnostic utility and predictive value of this technique.
Main Methods:
- Magnification hand angiography performed on 48 Raynaud's patients and 7 controls.
- Studies included cold exposure before and after intraarterial reserpine administration.
- Angiographic findings were correlated with clinical responses to vasodilator therapy.
Main Results:
- Most Raynaud's patients showed basal vasoconstriction and cryogenic vasospasm.
- Reserpine administration reduced both basal and cryogenic vasospasm in most patients.
- Angiographic improvement correlated with clinical response to long-term vasodilator therapy.
Conclusions:
- Hand angiography combined with cold exposure and post-reserpine studies is a valuable diagnostic tool for Raynaud's syndrome.
- This technique aids in predicting the efficacy of long-term vasodilator therapy.
- The findings support its use in clinical decision-making for Raynaud's patients.