Related Experiment Videos
Insulin and growth factors adaptation to normal puberty
M O Savage1, C P Smith, D B Dunger
1Department of Endocrinology, St. Bartholomew's Hospital, London, UK.
Hormone Research
|January 1, 1992
Abstract:
Insulin and IGF-1 production were measured throughout childhood and puberty and into adult life. Basal insulin and IGF-1 secretion increased during puberty, falling back to prepubertal levels in adulthood. However, fasting glucose levels remained constant, implying an increase in tissue resistance to insulin coinciding with puberty.