Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Humoral immune responses in osteomyelitis.

V P Bansal1, P K Mittal, G Ashokraj

  • 1Central Institute of Orthopaedics, New Delhi, India.

International Orthopaedics
|January 1, 1992
PubMed
Summary

Most osteomyelitis patients show a subdued immune response, with immunoglobulin levels failing to rise during infection. This suggests a potential immunodeficient state in individuals with osteomyelitis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of indoor residual spray and insecticide treated bed nets in a malaria endemic area of Santhal Pargana, Dumka district (Jharkhand).

The Journal of communicable diseases·2014
Same author

Establishment of a focus on Anopheles fluviatilis, an important malaria vector near the National Thermal Power Corporation Project in Dadri CHC area in District Gautam Budh Nagar, Uttar Pradesh, India: a case study.

Journal of vector borne diseases·2014
Same author

Insecticide susceptibility status of Phlebotomus argentipes, a vector of visceral leishmaniasis in different foci in three states of India.

Journal of vector borne diseases·2013
Same author

Field evaluation of Icon®Life, a long-lasting insecticidal net (LLIN) against Anopheles culicifacies and transmission of malaria in District Gautam Budh Nagar (Uttar Pradesh), India.

Journal of vector borne diseases·2012
Same author

Susceptibility of malaria vectors to insecticides in Gadchiroli district (Maharashtra), India.

Journal of vector borne diseases·2012
Same author

Wash resistance and efficacy of Olyset net and Permanet 2.0 against Anopheles stephensi in India.

Journal of the American Mosquito Control Association·2012

Area of Science:

  • Immunology
  • Infectious Diseases
  • Orthopedics

Background:

  • Osteomyelitis is a serious bone infection.
  • The immune response in osteomyelitis is not fully understood.
  • Immunoglobulin levels may indicate immune status during infection.

Purpose of the Study:

  • To investigate serum immunoglobulin levels (IgA, IgM, IgG) in patients with osteomyelitis.
  • To correlate immunoglobulin levels with clinical parameters of osteomyelitis.
  • To assess the immune response in osteomyelitis patients.

Main Methods:

  • Sera from 53 osteomyelitis patients and 23 controls were analyzed for IgA, IgM, and IgG levels.
  • Patients were categorized by disease duration, bone/part involved, etiology, activity, severity, and stage.
  • Correlative studies were performed between immunoglobulin levels and clinical parameters.

Main Results:

  • Serum immunoglobulin levels (IgA, IgM, IgG) generally did not exceed normal ranges in infected patients.
  • Immunoglobulin levels showed no significant variation concerning clinical parameters.
  • A subdued immune response was observed in most osteomyelitis patients.

Conclusions:

  • Most osteomyelitis patients exhibit a subdued immune response to the infection.
  • Findings suggest a possible underlying immunodeficient state in osteomyelitis.
  • Further research into immune status in osteomyelitis is warranted.

Related Experiment Videos