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Pyoderma gangrenosum treated with hyperbaric oxygen therapy.

V Wasserteil1, S Bruce, S L Sessoms

  • 1Department of Dermatology, Baylor College of Medicine, Houston, Texas 77030.

International Journal of Dermatology
|August 1, 1992
PubMed
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Hyperbaric oxygen therapy may effectively treat pyoderma gangrenosum, even in complex cases. This treatment aided wound healing and allowed for reduced corticosteroid use in a patient with rheumatoid arthritis and diabetes.

Area of Science:

  • Dermatology
  • Wound Healing
  • Hyperbaric Medicine

Background:

  • Pyoderma gangrenosum (PG) management often involves systemic immunosuppressants.
  • Treatment responses can be inconsistent, causing patient and physician frustration.
  • Hyperbaric oxygen therapy (HBOT) has been reported as a potential treatment for PG.

Observation:

  • A patient with severe rheumatoid arthritis and diabetes mellitus presented with pyoderma gangrenosum.
  • Standard systemic therapies were considered.
  • The patient underwent hyperbaric oxygen therapy.

Findings:

  • Hyperbaric oxygen therapy promoted the healing of pyoderma gangrenosum lesions.
  • HBOT enabled a reduction in the patient's systemic corticosteroid dosage.

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  • This suggests HBOT can be an effective adjunctive therapy for PG.

    • Implications:

    • Hyperbaric oxygen therapy offers a potential therapeutic option for pyoderma gangrenosum.
    • HBOT may reduce the need for systemic immunosuppression in managing PG.
    • This approach could improve patient outcomes and quality of life.