Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dose determination in high dose-rate brachytherapy.

P V Houdek1, J G Schwade, X Wu

  • 1Department of Radiation Oncology, University of Miami School of Medicine, FL 33103.

International Journal of Radiation Oncology, Biology, Physics
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Application of robotic stereotactic radiotherapy to peripheral stage I non-small cell lung cancer with curative intent.

Clinical oncology (Royal College of Radiologists (Great Britain))·2009
Same author

A novel applicator for low-dose-rate brachytherapy of gynecological cancers.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2003
Same author

Radiation recall dermatitis induced by methotrexate in a patient with Hodgkin's disease.

American journal of clinical oncology·2000
Same author

Pre-irradiation evaluation and management of brain metastases. American College of Radiology. ACR Appropriateness Criteria.

Radiology·2000
Same author

Solitary brain metastasis. American College of Radiology. ACR Appropriateness Criteria.

Radiology·2000
Same author

Multiple brain metastases. American College of Radiology. ACR Appropriateness Criteria.

Radiology·2000

A new model calculates the true dose from moving radiation sources in high dose-rate brachytherapy. This dynamic dose component is crucial for accurate treatment planning and avoids significant dosimetric errors.

Area of Science:

  • Medical Physics
  • Radiation Oncology

Background:

  • High dose-rate brachytherapy utilizes moving radiation sources.
  • Current software inadequately models dose from moving sources, using only stationary source simulations.

Purpose of the Study:

  • To develop a practical model for calculating the total dose delivered by a moving radiation source in brachytherapy.
  • To quantify the impact of the dynamic dose component on treatment accuracy.

Main Methods:

  • Developed an algorithm to calculate both dynamic (moving source) and static (dwell point) dose components.
  • Integrated calculations for dose delivered during source transit within and outside the implanted volume.

Main Results:

  • The dynamic dose component consistently increases dose at prescription points.

Related Experiment Videos

  • This component significantly distorts the overall dose distribution.
  • Dosimetric errors can range from <1% to over 10% if the dynamic component is ignored.
  • Conclusions:

    • A formalism for calculating dose from moving brachytherapy sources is essential.
    • Ignoring the dynamic dose component leads to significant inaccuracies in treatment planning.
    • The developed model provides a more accurate determination of the true, total administered dose.