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New antiviral antibiotics, cycloviracins B1 and B2. II. Structure determination
M Tsunakawa1, C Kotake, T Yamasaki
1Bristol-Myers Squibb Research Institute, Tokyo, Japan.
The Journal of Antibiotics
|September 1, 1992
Abstract:
The structures of novel antiviral antibiotics, cycloviracins B1 and B2 have been determined by means of chemical and spectroscopic methods including 2D NMR correlation spectroscopy. The antibiotics are unique macrocyclic diesters consisting of two D-glucoses, three 2-O-methyl-D-glucoses and two (C24 and C26) hydroxy fatty acids.