[Spermatogonia counts in descended and undescended prebuberal testes (author's transl)]

The following conclusions which show the importance of time of medical treatment resulted from the examination of 288 testicular biopsies (including 46 controls) by statistical analysis in correlation to age. 1. There is no difference in the number of spermatogonia per tubule cross section of descended and undescended testes in children from birth to 2 years of age. 2. The number of spermtogonia in descended testes is not different in children from birth to 2 years in comparison to children aged 2-6 years. 3. A statistically significant decrease of spermatogonia takes place in the undescended testes of children from 2-6 years in comparison to children from birth to 2 years. 4. The difference in the number of spermatogonia of descended and undescended testes increases in children above the age of 2. It must be concluded from this study that the pathological alterations of the germinative epithelium increase in children beyond the age of 2. Assuming that pathological alterations of the germinative epithelium are caused by the dystopy of the testes, medical treatment should be carried out before the child is more than 2 years old.