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Published on: June 14, 2021
[Persistent hyperplastic primary vitreous. Middle-term results of vitrectomy]
1Clinique Ophtalmologique Universitaire B, UER Lyon Nord, Hôpital de la Croix-Rousse.
Insights
Pars plana lensectomy and vitrectomy effectively treated persistent hyperplastic primary vitreous in children. This surgery prevented serious complications and improved visual and aesthetic outcomes.
Area of Science:
- Ophthalmology
- Pediatric Surgery
Context:
- Persistent hyperplastic primary vitreous (PHPV) is a congenital condition affecting vision.
- Complete anterior and posterior PHPV presents significant management challenges.
Purpose:
- To evaluate the efficacy of pars plana lensectomy and vitrectomy for complete PHPV.
- To assess surgical outcomes, complications, and long-term effects.
Summary:
- Seven children with complete PHPV underwent pars plana lensectomy and vitrectomy.
- All patients experienced beneficial outcomes without complications.
- The surgery prevented neovascular glaucoma, vitreous hemorrhages, and phtisis bulbi.
Impact:
- Surgical intervention led to improved aesthetics, including resolution of leucocoria and reduced microphthalmos.
- Correction of strabismus was observed in some cases.
- Good visual recovery was achieved, contingent on the absence of retinal malformations.
Abstract:
In this study, the authors present a homogeneous series of seven children suffering from persistent hyperplastic primary vitreous, in its complete anterior and posterior form. These children were operated by pars plana lensectomy and vitrectomy. The surgical operation was beneficial in every case: not only were there no complications, but the operation also prevented progression towards neovascular glaucoma, vitreous hemorrhages and phtisis bulbi. In addition, one of the benefits of this technique was esthetic, with the disappearance of leucocoria, the occasional correction of strabismus and the reduction in microphthalmos. Visual recovery can be surprisingly good, in the absence of any associated retinal malformation.

