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[Post-menopausal osteoporosis. Epidemiologic aspects].

V Ringa1, G Bréart

  • 1INSERM U 149, Villejuif.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|January 1, 1992
PubMed
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Post-menopausal osteoporosis affects millions, causing fractures and high costs. Current risk factors lack accuracy, necessitating better screening and prevention strategies for women’s health.

Area of Science:

  • Epidemiology
  • Gerontology
  • Public Health

Context:

  • Osteoporosis is a widespread condition characterized by fragility fractures, significantly impacting women's quality of life.
  • In France, an estimated one million women suffer from vertebral fractures, highlighting a substantial public health concern.
  • The economic burden of osteoporosis is considerable, with hip fractures alone costing 4 billion francs annually in France.

Purpose:

  • To outline the epidemiological characteristics of post-menopausal osteoporosis, focusing on fracture incidence and severity.
  • To review current screening methods and preventive strategies for osteoporotic fractures in post-menopausal women.
  • To address the underutilization of estrogen therapy, the only universally agreed-upon preventive treatment.

Summary:

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  • Current methods for identifying women at high risk of osteoporotic fractures, including clinical history, biological markers, and bone mass measurements, lack sufficient sensitivity and specificity.
  • Estrogen therapy, despite being the only universally accepted preventive treatment, is used by only 8% of French menopausal women.
  • Further research is needed to clarify the effects of combined estrogen and progestogen treatments on cardiovascular disease and breast cancer risks.

Impact:

  • Highlights the need for improved diagnostic tools and risk stratification for osteoporosis.
  • Emphasizes the importance of addressing barriers to effective osteoporosis prevention and treatment in post-menopausal women.
  • Calls for specific research into the safety profiles of combined hormone therapies for osteoporosis management.