[Functional characteristics of hypertrophic cardiomyopathy]

The hemodynamics was studies in 59 patients with hypertrophic cardiopathy: obstructive (33 cases) and non-obstructive (26 cases). The diagnosis was made and the hemodynamics studied by left and right ventricle catheterization, left ventriculography and echocardiography. A general hyperkinetism of the left ventricle pump function was established--increased fraction of forcing, per cent of the systolic shortening and contraction rate of the circumferential fibres with a not adequately large beat and minute volume. The regional functional of the left ventricle is characterized by hypokinetism of the interventricular septum and considerable hypercontractility of the left ventricle free wall. The diastolic filling of the left ventricle is impeded due to the decreased telediastolic size and volume and diminished extensibility. That leads to the increase of the final diastolic pressure in the left ventricle and the pulmonary artery, manifested especially after physical loading. The subaortic constriction is a result mainly of the systolic shifting of the posterior papillaris muscle forward and upward towards the hypertrophic interventricular septum. Subaortic stenosis shows considerable deviations and changes during the dynamic observations of the patients.