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Allergic aspergillus sinusitis with proptosis

K J Daghistani1, T S Jamal, S Zaher

  • 1Department of Otorhinolaryngology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

The Journal of Laryngology and Otology
|September 1, 1992
PubMed

Insights

Allergic aspergillus sinusitis, a fungal infection, presents with sinus masses and eye proptosis. Prompt surgical intervention is crucial for treatment and preventing recurrence.

Area of Science:

  • Otolaryngology
  • Allergy and Immunology
  • Radiology

Background:

  • Allergic aspergillus sinusitis (AAS) is an increasingly recognized fungal infection of the paranasal sinuses.
  • It often presents with symptoms mimicking other sinonasal pathologies, including malignancy.

Observation:

  • This study reviewed five cases of AAS presenting with proptosis, allergic rhinitis symptoms, and radiological evidence of expansile sinus masses.
  • Surgical findings included greenish, cheesy material within the sinuses.

Findings:

  • Histological examination revealed eosinophils, Charcot-Lyden crystals, and septate hyphae consistent with Aspergillus fumigatus infection.
  • All five patients had Aspergillus fumigatus cultured from surgical specimens.

Implications:

  • Allergic aspergillus sinusitis can mimic malignant sinonasal disease, necessitating its inclusion in differential diagnoses for complex sinus lesions and proptosis.
  • Surgical management involving removal, drainage, and aeration is effective, though recurrence is possible.

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