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Dilating cardiomyopathy as the expression of Xp21 Becker type muscular dystrophy
L Palmucci1, C Doriguzzi, T Mongini
1Paolo Peirolo Centre for Neuromuscular Diseases, University of Turin, Italy.
Journal of the Neurological Sciences
|September 1, 1992
Abstract:
A 35-year-old man with severe progressive dilating cardiomyopathy and no clinical signs of muscle disease underwent muscular investigations because of markedly increased serum creatine kinase. Muscle biopsy demonstrated Becker type muscular dystrophy with dystrophin of low molecular weight. Genetic analysis showed a deletion spanning from exon 45 to exon 46 in the Xp21 region. Xp21 Becker type muscular dystrophy must be considered in the differential diagnosis of dilating cardiomyopathy.